This is a solution of Case Study Research part 2 in which we discuss which entire research has been conducted is explained.

Background of the study:

Case Study Research part 2

The study is basically based on the differences between the densely somatotroph adenomas and the sparsely somatotroph adenomas. As per the viewpoint of Webb (1998, .421), adenomas are the tumours that occurs in the epithelial tissue of an organ. The glands giving rise of adenomas are the pituitary gland, prostate, adrenal gland and the thyroid. It is seen that often adenomas develop from the non glandular areas though the tissue structure is of granular type. As per Sam and Meeran (2009, p.452), clinical expression of the two subtypes of somatotroph adenomas are different that makes them achieve uniqueness.


The issue identified is the adenoma which generally develops due to the mutation in the gsp gene. Several other reasons are also present that influences its occurrence. However, it is known that there are two subtypes of somatotroph adenomas that affect a person. The issue arises in the benign tumors turning malignant through stimulating factors. As observed in the study of Sheppard and Stewart (2002, p.754), malignant adenomas are different in expression in the clinical sector as is studied in the theoretical knowledge. This reflects on the differences of genetic expression of the two subtypes that creates hindrances in developing the suitable treatment. It is seen that about 18% of people has been affected by the sparsely somatotroph adenomas as compared to the densely adenomas (PHIFER and SPICER, 2011, p.1220). This creates the attention of the researcher to identify the differences at the molecular level to resolve the issue of clinical manifestation of the disease. In addition, very few studies have presented differences of these two subtypes with lacking in the sector of molecular and gene expressional differences.

Contribution of Research

The study as is based on differences, hence, it will help in conducting future studies of identifying the possible treatments of densely situated adenomas in comparison with the sparsely situated adenomas. As adenomas are related to the tumor, therefore, from this case study future researchers can generate knowledge on genetic basis that has been the major cause of these tumor to develop suitable treatments for benefiting human health. In addition, comparative studies on clinical expression and molecular analysis of the two subtypes can be carried out from this study.

Data collection sources

This piece of course work is based on the information obtained from the secondary sources. Secondary sources that comprise of the journals and books provide enormous knowledge on the research topic. In addition, as case studies has been used, therefore, they have been collected from the secondary sources particularly journals from different database.

Method outline

In executing this research, suitable methods have been used for achieving the quality outcomes. In the process of data collection and analysis, the researcher have made use of the positivism philosophy, inductive approach and the descriptive design. Inclusion and exclusion criteria has been implemented in selecting the journal articles from the database for obtaining better outcomes.


This chapter covers the background information on adenomas with the reason of selecting this research topic. Based on the aim and objectives developed in this section, the researcher have performed the entire work by gaining note on the difference of the two subtype of somatotroph adenomas.

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